Zika’ s hideouts

Zika virus may remain in the cerebrospinal fluid and lymph nodes associated with rhesus monkeys long after any symptoms have dissipated, experts at Harvard Medical School reported in Cell this week (April 27). “ Until recently, everyone was focused on the acute [infection]— what goes on when a person gets infected initially by a mosquito taste. But what this paper tells us is that maybe, 8 weeks down the line, symptoms could manifest from this later stage associated with virus replication in the central nervous system and other sites, ” Andres Pekosz of the Johns Hopkins Bloomberg School of Community Health in Baltimore who was not involved in the research informed The Scientist . “ Right now, we might be missing some of the disease associated with infection because we’ re not looking far enough down the path. ”

More-advanced mini brains

2 groups of scientists have developed some of the most-advanced mini brains, or even organoids, to date. The teams described their in vitro models in two papers published in Nature this week (April 26). “[T]he human pluripotent stem cells are plastic sufficient to generate the diversity of cells necessary to recreate human being, early stages of neurodevelopment in a dish, ” noted Alysson Muotri of the University of California, San Diego, who was not really involved in either study. “ Every neuroscientist working with earlier brain development will be excited by reading these posts. ”

Science marches

Thousands of people marched for science worldwide last weekend (April 22). The Scientist talked with demonstrators in Berlin, Chicago, and Washington, DC. Many indicated it was their first time speaking publicly regarding the importance of science. “ I’ ve never done this particular and I am so excited to be here, ” caterer Peggy Mikros told The Scientist at the Chicago march, adding that the event has motivated her to continue advocating for science.

Following the DC march, Rush Holt, CEO of the American Organization for the Advancement of Science (AAAS), an organization that joined with the March for Science, said he felt the big event was a success— even before people arrived in the nation’ h capital to demonstrate.

In case you missed them, take a look at The Scientist ’ s video clip from the national march, plus a selection of signs from technology supporters we spoke with on the ground in Berlin, Chi town, and DC.

Tomorrow (April 29), a few science supporters will take to the streets of DC yet again, for the People’ s Climate March on Washington.

Other news in life science

Artificial Womb Supports Premature Fetal Lamb Development
The lungs of extremely early lambs supported in a closed, sterile environment that enables fluid-based gas exchange grow and develop normally, researchers review.

Cell Lines Gain Cancer-Related Mutations
A screen of human embryonic stem cellular lines finds several that accumulated changes in the gene TP53, including aberrations commonly observed in cancer.

Tissue-Clearing Technique Works on Bone
CLARITY made mouse bones transparent while conserving fluorescent labels so researchers could visualize tagged osteoprogenitors.

Genetic Analysis Reveals the Evolutionary Great Dogs
By analyzing the genomes associated with 161 dog breeds, scientists discover how and when certain canine bread of dogs emerged.

Another New Timeline for Homo naledi
The historic human may have lived around 200, 000 to three hundred, 000 years ago— much more recently than previously approximated.