John is a 48-year-old Caucasian male with a history of osteo-arthritis secondary to trauma suffered as a collegiate athlete. He or she loves playing catch with his sons, but his Acromioclavicular (AC joint) arthritis, as well as a right shoulder cartilage rip, made this father and son playtime a painful occasion to endure. An X-ray revealed right AC combined hypertrophy and degenerative changes. An MRI of the correct shoulder read, “ towards the inferior aspect of the glenohumeral joint, an approximately 4mm defect along the anterior element of the glenoid cartilage is associated with a labral tear”. Sara didn’ t want to give up the valuable bonding process of playing catch with his sons. John put his rely upon the science and application of stem cell therapy that has shown to help heal and repair torn cartilage, in addition to reduce the arthritic response of the joints.
Autologous stem cells harvested from adipose cells were utilized. In this procedure 200c of adipose tissue is collected from the body in a “ Mini-Liposuction” procedure. The procedure is known as a “ mini-“ liposuction because the amount of adipose cells needed to be removed in order to harvest stem cells is substantially less than required to do a liposuction whose purpose is body fat removal for cosmetic/ weight reduction purposes. Along with processing associated with adipose tissue to extract stem cells, Platelet Wealthy Plasma (PRP) was prepared at the same time. Injections of come cells and a PRP suspension were placed into the correct AC joint as well as into the right shoulder capsule. Within the weeks following the procedure John reported a continued enhancement in pain at both his AC joint and also in his shoulder. John’ s response to treatment was simple to evaluate because a throwing motion, playing football, produced discomfort every single time. He describes his result as very effective in terms of the reduction of pain and ease of motion from the right shoulder.
Jason was obviously a 16-year-old with Crohn’ s Disease, whose parents introduced him in for consultation having been advised to begin steroid therapy as the standard treatment for his condition. His household wished to avoid long-term steroid therapy and hoped to get an alternative. Testing revealed multiple food sensitivities. Strict prevention of food allergens was able to improve Jason’ s situation symptomatically, however repeat colonoscopies showed after several years, that this underlying Crohn’ s disease was still progressing. The particular patient’ s gastroenterologist advised the patient to begin a “ biologic” medication. With the known serious side effects of the biologic medications available for autoimmune disease, Jason and his parents chosen giving stem cell therapy a try.
To be able to harvest stem cells a bone marrow cell removal was performed. This is another way to derive stem cells, in this instance mesenchymal cells. This is used as an alternative to adipose tissue removal in a person who is deemed too thin to get enough belly fat to harvest the amount of stem cells required. For Jason’ s autoimmune condition an intravenous infusion of saline with stem cells was given. Mesenchymal stem cells are actually shown to have immunomodulating effects. They inhibit the service of lymphocytes and the production of inflammatory substances which usually characterize the pathophysiology of autoimmune disease.
Within a few days of his treatment the breakout associated with abdominal/rectal pain and rectal bleeding he had experienced immediately before the procedure quickly resolved. Also, Jason observed which the long standing eczema he has also suffered from was obviously improving as well. Jason and his parents will be awaiting an upcoming colonoscopy to judge the impact of his stem cellular treatment on the progression of his underlying Crohn’ h disease. Meanwhile, their assessment of his stem cellular treatment is that it was very successful. He states this individual feels better than he has in many years.
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Image Sources: Stem Cell, Crohn’ s Condition
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