A brand new blood system isn’ t created from scratch— just some thing close to it. A single type of stem cell, a new research demonstrates, can fully repopulate the bone marrow and provide rise to all the cell lineages that constitute an entire blood system.

This blood-forming stem cell is recognized by three cell-surface markers— or rather the presence of 2 markers and the absence of a third. By heeding these guns, scientists may improve transplantation procedures, as well develop much better gene therapy and gene-editing approaches.

The discovery had been described November 1 in the journal Science Translational Medication, in an article entitled “ A Distinct Hematopoietic Stem Cellular Population for Rapid Multilineage Engraftment in Nonhuman Primates. ” According to this article, CD34-positive hematopoietic stem cells (HSCs), long considered the gold standard for stem cellular therapy and transplantation of stem cell– enriched grafts, do not all contribute to multilineage engraftment. In fact , few of…