The current research market of cell separation is hugely dominated by three companies – Stem Cell Technologies (Canada), Miltenyi Biotec (Germany) and Thermo Fisher (Dynal brand). Everyone, who involved in cell research, knows these brands and use their products. After 2 decades, magnetic cell separation methods, developed by these companies, became “conventional” or standard in research. Today, I’d like to look beyond “conventional” brands and briefly overview new comers to the world of cell separation. New companies with new technologies are diversifying the market and offering some advantages. I’d like crowdsource here – please feel free to add new companies if I missed them.
German company, which offers non-magnetic cell isolation kits and reagents for researchers. Competitive advantage of their technology is simultaneous and/ or sequential isolation of multiple cell populations.
Learn more from video tutorials.
Also, check this protocol: Cascade System for Simultaneous Separation of Multiple Cell Types
US-based startup, which entered cell separation market last year. Company offers hydrogel-based technology for magnetic tag-free cell separation. Competitive advantages, listed by company.
US-based company, founded in 2012. Akadeum offers new non-magnetic technology for cell separation – buoyancy-activated cell sorting (BACS). Buoyancy technology entails microscopic microbubbles, which float on a surface of the liquid after capturing targeted cells. Competitive advantages – simplicity, speed and magnet/ device independence.
US-based company, which offers improved magnetic cell isolation. Company makes ferrofliuds (nano-magnetic liquids) and magnetic devices. Competitive advantage – increased efficiency and purity due to special qualities of ferrofluids.
Spinout of Georgia Tech, utilizing microfluidic-based technology. Company offers label-free isolation of adherent cells in microfluidic chamber. Competitive advantages – label-free, speed (95% purity in 5 min) and focus on adherent cells.
Israeli company, founded in 2006. BioCEP offers improved automated magnetic cell separation. Competitive advantage is highly pure isolation of rare cell populations.
If you had a chance to try cell separation systems, mentioned in this post, please share your experience!