Author: Mira Swave MD

Stem Cell Muscle Patch for Heart Failure

Scientists are testing a pathbreaking technique to treat heart failure. Using a muscle patch made from the patient’s own stem cells, the researchers have succeeded in repairing damaged hearts with promising results. What is heart failure? When the heart can no longer properly perform its function of pumping blood to the body, it is termed heart failure. It is estimated that more than 5.5 million Americans are living with heart failure. The condition is responsible for approximately 1 out of 9 deaths in the country. There are several underlying causes of heart failure. Diabetes, high blood pressure, and coronary...

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Researchers Create Cells Resistant to HIV

Researchers at The Scripps Research Institute, a not-for-profit biomedical research facility, have developed a new approach to make cells resistant to the HIV virus. In laboratory experiments, the HIV-resistant cells promptly replaced infected cells. The method offers a potential cure for people with HIV. The findings were published in Proceedings of the National Academy of Sciences. Long-Term Protection and Cure for HIV Senior staff scientist and co-author of the study, Jia Xie, explains the approach would offer long-term protection from the virus. In this method, antibodies to HIV are tethered to immune cells, thus creating a population of cells...

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Salk Institute Scientists Expand Stem Cell Abilities

In the laboratory, pluripotent stem cells have embryo-like abilities to develop into different types of tissues found in the human body. However, it is only totipotent stem cells that can develop into embryo-supporting tissues such as the placenta. Since extra-embryonic tissues play an important role in healthy growth and development, scientists at Salk Institute have been trying to discover how human stem cells can be prompted to generate extra-embryonic tissues in addition to embryonic tissues. Salk Institute Scientists Expand Stem Cell Abilities Working in collaboration with scientists from China’s Peking University, investigators at the Salk Institute in La Jolla,...

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Stanford Study Finds Key Protein in Injury Repair

A study at the Stanford University School of Medicine has revealed that a single protein is key in priming stem cells to respond to injury. Experiments in mice showed that the primer protein helped in quicker recovery from muscle injury. In fact, the skin also healed more rapidly and hair grew back quicker in the mice treated with the protein. Scientists hope to apply these findings to help people recovering from surgery and perhaps to restore youth to aging stem cells. Wound Healing Following Trauma and Aging Professor of Neurology and Neurological Sciences, Thomas Rando, M.D., Ph.D., explains that...

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Stem Cell Experiments for Brain Repair Drugs

Researchers at the University of Portsmouth have collaborated with biologists at the University of Zurich and University of Lyon to discover drugs for brain repair. The team has identified drugs that activate signals to specific types of cells in the adult neurological system. The experiments in mouse models may prove useful in developing treatments of degenerative disorders for the human brain. Neuron Development in Adults Neurons and oligodendrocytes (supporting cells) develop in the forebrain near the ventricles in adults. This subventricular zone of neuron formation contains neural stem cells that give rise to different cell types. The transcriptional changes...

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